Functional stoichiometric analysis of metabolic networks
نویسندگان
چکیده
منابع مشابه
Stoichiometric analysis of metabolic networks
A major current challenge in systems biology is to clarify the relationship between structure, function and regulation in complex metabolic networks reconstructed from genomic data. However, dynamic mathematical modeling of large-scale networks meets difficulties as the necessary mechanistic detail and kinetic parameters are rarely available. In contrast, structure-oriented (stoichiometric / co...
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Metabolic engineering tools have been widely applied to living organisms to gain a comprehensive understanding about cellular networks and to improve cellular properties. Metabolic flux analysis (MFA), flux balance analysis (FBA), and metabolic pathway analysis (MPA) are among the most popular tools in stoichiometric network analysis. Although application of these tools into well-known microbia...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2005
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/bti674